Fresh vs Frozen vs Lyophilized Fecal Microbiota transplant for Recurrent Clostridium Difficile Infection:

Lyophilized Fecal Microbiota Transplantation Capsules for Recurrent Clostridium difficile Infection

Oral, frozen fecal microbiota transplant (FMT) capsules for recurrent Clostridium difficile infection

BACKGROUND Fecal microbiota transplantation (FMT) has been shown to be safe and effective in treating refractory or relapsing C. difficile infection (CDI), but its use has been limited by practical barriers. We recently reported a small preliminary feasibility study using orally administered frozen fecal capsules. Following these early results, we now report our clinical experience in a large c...

Clostridium difficile Infection and Fecal Microbiota Transplant.

Clostridium difficile infection (CDI) is a major source of morbidity and mortality for hospitalized patients. Although most patients have a clinical response to existing antimicrobial therapies, recurrent infection develops in up to 30% of patients. Fecal microbiota transplant is a novel approach to this complex problem, with an efficacy rate of nearly 90% in the setting of multiple recurrent C...

1798Oral, Frozen Fecal Microbiota Capsules for Relapsing Clostridium difficile Infection

1798. Oral, Frozen Fecal Microbiota Capsules for Relapsing Clostridium difficile Infection Ilan Youngster, MD; George Russell, MD; Christina Pindar,; Jenny Sauk, MD; Elizabeth Hohmann, MD; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Division of Infectious Diseases, Boston Children’s Hospital, Boston, MA...

Fecal microbiota transplant protocol for clostridium difficile infection.

Fecal microbiota transplant has become more acceptable as a therapeutic for recurrent Clostridium difficile infection. The FDA has an enforcement discretion policy for practitioner's performing this therapy, which includes informed consent for this experimental treatment. This manuscript describes a typical procedure that can be followed that includes the important aspects of this preparation a...